BDBM50425382 CHEMBL2316197

SMILES COC(=O)CC[C@H](NC(=O)c1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1)C(=O)OC

InChI Key InChIKey=STTSHEDSPVREJI-VWLOTQADSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50425382   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50425382(CHEMBL2316197)
Affinity DataIC50:  18nMAssay Description:Inhibition of p38alpha MAP kinase in whole blood (unknown origin) assessed as lipopolysaccharide-stimulated TNF-alpha release by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50425382(CHEMBL2316197)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50425382(CHEMBL2316197)
Affinity DataIC50:  5nMAssay Description:Inhibition of p38alpha MAP kinase (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed