BDBM50428738 CHEMBL2333163::Sesquibastadin 1

SMILES Oc1ccc(CCNC(=O)C(Cc2cc(Br)c(O)c(Oc3ccc(CCNC(=O)C(Cc4cc(Br)c(O)c(c4)-c4cc(CC(N=O)C(=O)NCCc5ccc(O)c(Br)c5)cc(Br)c4O)N=O)cc3Br)c2)N=O)cc1Br

InChI Key InChIKey=HJVFTUSVRMGBLM-UHFFFAOYSA-N

Data  21 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50428738   

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of CDK2/cyclin-A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of aurora-B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of ARK5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of aurora-A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of COT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  600nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of EPHB4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of ERBB2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of INSR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  800nMAssay Description:Inhibition of MET (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of PDGFR-beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  700nMAssay Description:Inhibition of SAK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  700nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  600nMAssay Description:Inhibition of TIE2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  600nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL
LigandPNGBDBM50428738(CHEMBL2333163 | Sesquibastadin 1)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of CDK4/cyclin-D1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed