BDBM50430960 CHEMBL2337400

SMILES Cc1c(CCOCCO[N+]([O-])=O)cc(-c2ccc(cc2)S(C)(=O)=O)n1-c1ccccc1

InChI Key InChIKey=IIFFGAKIUNZWTM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50430960   

TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50430960(CHEMBL2337400)
Affinity DataIC50:  17nMAssay Description:Inhibition of Escherichia coli lipopolysaccharide-induced COX2 activity in mouse J774 cells assessed as decrease in PGE2 levels after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50430960(CHEMBL2337400)
Affinity DataIC50:  17nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50430960(CHEMBL2337400)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50430960(CHEMBL2337400)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of arachidonic acid-induced COX1 activity in mouse J774 cells assessed as decrease in PGE2 levels incubated for 15 mins prior to arachidon...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed