BDBM50431494 CHEMBL2348672

SMILES COc1ccccc1C1CCCN1C(=O)C(Nc1ccccc1F)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=IGZJKPXTCRCOHK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50431494   

TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50431494(CHEMBL2348672)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at dog TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium influx incubated for 5 mins prior to icil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed