BDBM50432208 CHEMBL2347110

SMILES COc1cc2N(O)C(=O)[C@@H](N)Cc2cc1Cc1ccccc1

InChI Key InChIKey=VVJIMJXLYKGRIQ-AWEZNQCLSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50432208   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50432208(CHEMBL2347110)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50432208(CHEMBL2347110)
Affinity DataIC50:  37nMAssay Description:Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed