BDBM50432360 CHEMBL2348175::US9616064, Compound 15b

SMILES Nc1nccc(n1)-n1ccc2ccc(F)cc12

InChI Key InChIKey=YCQDQQRGBMNFGC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50432360   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50432360(CHEMBL2348175 | US9616064, Compound 15b)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM50432360(CHEMBL2348175 | US9616064, Compound 15b)
Affinity DataIC50:  1.70E+3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM50432360(CHEMBL2348175 | US9616064, Compound 15b)
Affinity DataIC50:  4.90E+3nMAssay Description:The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50432360(CHEMBL2348175 | US9616064, Compound 15b)
Affinity DataIC50:  156nMAssay Description:Inhibition of CDC7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed