BDBM50432641 CHEMBL2347378

SMILES OC(=O)C[C@H]1C[C@H]([C@@H](N(CC2CC2)C1=O)c1ccc(Cl)cc1)c1cccc(Cl)c1

InChI Key InChIKey=OMAPWASVHLHIRY-AGHHOFFYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50432641   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50432641(CHEMBL2347378)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human recombinant GST-thrombin-MDM2 (1 to 188) expressed in Escherichia coli assessed as reduction of MDM2-p53 interaction incubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50432641(CHEMBL2347378)
Affinity DataIC50:  2.75E+4nMAssay Description:Inhibition of human recombinant GST-thrombin-MDM2 (1 to 188) expressed in Escherichia coli assessed as reduction of MDM2-p53 interaction incubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed