BDBM50432647 CHEMBL2347387::US11407721, Example 14 Step A
SMILES Clc1ccc(cc1)[C@@H]1[C@@H](O[C@@H](CC=C)C(=O)N1CC1CC1)c1cccc(Cl)c1
InChI Key InChIKey=GYOAZTPSRBBAKY-BDTNDASRSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50432647
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant GST-thrombin-MDM2 (1 to 188) expressed in Escherichia coli assessed as reduction of MDM2-p53 interaction incubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 5.10E+4nMAssay Description:This assay was run using the same conditions as the HTRF1 assay except that 20 uL of GST-hMDM2 was incubated with 1.0 ul of diluted compound.More data for this Ligand-Target Pair
Affinity DataIC50: 1.34E+3nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant GST-thrombin-MDM2 (1 to 188) expressed in Escherichia coli assessed as reduction of MDM2-p53 interaction incubated fo...More data for this Ligand-Target Pair