BDBM50432661 CHEMBL2347398::US11407721, Example 1 Step B
SMILES CN1[C@@H]([C@@H](OCC1=O)c1ccc(Br)cc1)c1ccc(Br)cc1
InChI Key InChIKey=OUTBUVLNDIYGFF-SJORKVTESA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50432661
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human recombinant GST-thrombin-MDM2 (1 to 188) expressed in Escherichia coli assessed as reduction of MDM2-p53 interaction incubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 3.46E+4nMAssay Description:This assay was run using the same conditions as the HTRF1 assay except that 20 uL of GST-hMDM2 was incubated with 1.0 ul of diluted compound.More data for this Ligand-Target Pair
Affinity DataIC50: 5.41E+3nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair