BDBM50433273 CHEMBL2376322

SMILES CCC1(C)NC(=O)c2cc(ccc2NC1=O)S(=O)(=O)Nc1ccccc1

InChI Key InChIKey=VCFIMVZQVDYSSN-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50433273   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433273(CHEMBL2376322)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant DGAT2 using dioleoyl-sn-glycerol and [14C]oleoyl coenzyme A as substrate after 30 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433273(CHEMBL2376322)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells using dioleoyl-sn-glycerol and [14C]oleoyl coenzyme A as substrate after 30 mins by liqu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433273(CHEMBL2376322)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of human recombinant MGAT3 expressed in insect cell membrane using 2-oleyl-sn-glycerol and [14C]-oleyl-coenzyme A as substrate after 10 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA wax alcohol acyltransferase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433273(CHEMBL2376322)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant AWAT1 expressed in insect cell membrane using palmitoleyl alcohol and [14C]stearoyl coenzyme A as substrate after 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50433273(CHEMBL2376322)
Affinity DataIC50:  158nMAssay Description:Inhibition of mouse recombinant MGAT2 expressed in insect cell membrane using 2-oleoyl-sn-glycerol and oleoyl coenzyme A as substrate after 40 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50433273(CHEMBL2376322)
Affinity DataIC50:  398nMAssay Description:Inhibition of human recombinant MGAT2 expressed in insect cell membrane using 2-oleoyl-sn-glycerol and oleoyl coenzyme A as substrate after 40 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA wax alcohol acyltransferase 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433273(CHEMBL2376322)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant AWAT2 expressed in insect cell membrane using cetyl alcohol and [14C]oleoyl coenzyme A as substrate after 10 to 15 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50433273(CHEMBL2376322)
Affinity DataIC50:  501nMAssay Description:Inhibition of human recombinant MGAT1 expressed in insect cell membrane using 2-oleyl-sn-glycerol and [14C]-oleyl-coenzyme A as substrate after 10 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed