BDBM50433867 CHEMBL2380401

SMILES CN([C@H]1CN(C[C@@H]1S)C(N)=O)S(=O)(=O)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=BTCYLUBBXQARQV-IRXDYDNUSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50433867   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))TBA
LigandPNGBDBM50433867(CHEMBL2380401)
Affinity DataKi:  62nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMatrix metalloproteinase-14(Homo sapiens (Human))TBA
LigandPNGBDBM50433867(CHEMBL2380401)
Affinity DataKi:  62nMAssay Description:Inhibition of MMP-14 (unknown origin) using Mca-PLGLDpa-AR-NH2 as substrate preincubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))TBA
LigandPNGBDBM50433867(CHEMBL2380401)
Affinity DataKi:  160nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMatrilysin(Homo sapiens (Human))
Florida State University

Curated by ChEMBL
LigandPNGBDBM50433867(CHEMBL2380401)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP-7 (unknown origin) using Mca-PLGLDpa-AR-NH2 as substrate preincubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Florida State University

Curated by ChEMBL
LigandPNGBDBM50433867(CHEMBL2380401)
Affinity DataKi: >2.50E+4nMMore data for this Ligand-Target Pair
In DepthDetails
Target72 kDa type IV collagenase(Homo sapiens (Human))TBA
LigandPNGBDBM50433867(CHEMBL2380401)
Affinity DataIC50:  2.30nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMatrix metalloproteinase-9(Homo sapiens (Human))TBA
LigandPNGBDBM50433867(CHEMBL2380401)
Affinity DataIC50:  1.30nMMore data for this Ligand-Target Pair
In DepthDetails