BDBM50434334 CHEMBL2386730::US9181275, 4

SMILES CC1=C(SC2=NCc3ccccc3CN12)c1ccc(OCCCN2CCOCC2)cc1

InChI Key InChIKey=CLOUPUVCLAWRNH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434334   

TargetHistamine H3 receptor(Rattus norvegicus (rat))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50434334(CHEMBL2386730 | US9181275, 4)
Affinity DataKi:  0.320nMAssay Description:Binding affinity to histamine H3 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50434334(CHEMBL2386730 | US9181275, 4)
Affinity DataKi:  0.324nM ΔG°:  -12.9kcal/moleT: 2°CAssay Description:To determine the effectiveness of representative compounds of this invention as histamine-3 receptor ligands (H3 receptor ligands), the following tes...More data for this Ligand-Target Pair
In DepthDetails US Patent