BDBM50439512 CHEMBL2418354

SMILES CCNC(=O)Nc1ccc(cc1)-c1nc(N2CCOC[C@@H]2C)c2nc(n(C)c2n1)C(C)(C)O

InChI Key InChIKey=CLQHPLAUSBFUDC-AWEZNQCLSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50439512   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50439512(CHEMBL2418354)
Affinity DataKi:  7nMAssay Description:Inhibition of human recombinant mTOR (1360-2549) expressed in insect cells assessed as phosphorylation of recombinant (GFP)-4-EBP1 after 30 mins by L...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50439512(CHEMBL2418354)
Affinity DataKi:  390nMAssay Description:Displacement of TAMRA-PIP3 from PI3Kalpha GRP-1 pleckstrin homology domain (unknown origin) assessed as formation of 3,4,5-inositoltriphosphate after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50439512(CHEMBL2418354)
Affinity DataKi:  490nMAssay Description:Displacement of TAMRA-PIP3 from PI3Kdelta GRP-1 pleckstrin homology domain (unknown origin) assessed as formation of 3,4,5-inositoltriphosphate after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed