BDBM50440538 CHEMBL2426174

SMILES O=C(Nc1nnc(s1)-c1ccncc1)Nc1ccc(-c2cn[nH]c2)c(c1)C#N

InChI Key InChIKey=PNYZVACPJDKKEE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50440538   

TargetRecQ-like DNA helicase BLM(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50440538(CHEMBL2426174)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of BLM (unknown origin) by gel-based DNA unwinding assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent DNA helicase Q1(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50440538(CHEMBL2426174)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of RECQ1 (unknown origin) by gel-based DNA unwinding assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Homo sapiens (Human))
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50440538(CHEMBL2426174)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of WRN (unknown origin) by gel-based DNA unwinding assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed