BDBM50443730 CHEMBL3093878::US9238658, 19

SMILES CNC(=O)c1cnc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)s1

InChI Key InChIKey=YYJUXAKSVQHVLO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50443730   

TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50443730(CHEMBL3093878 | US9238658, 19)
Affinity DataIC50:  93nMAssay Description:Inhibition of SCD1 in Sprague-Dawley rat liver microsomes using Stearoyl-[9,10-3H]-CoA as substrate assessed as [3H2O] generationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50443730(CHEMBL3093878 | US9238658, 19)
Affinity DataIC50:  93nMT: 2°CAssay Description:The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...More data for this Ligand-Target Pair
In DepthDetails US Patent