BDBM50444400 CHEMBL3094479

SMILES CCC(Cc1cccc2ccccc12)NS(=O)(=O)c1c(C)cc(C)cc1C

InChI Key InChIKey=SGPHLLUCLSONGK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50444400   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444400(CHEMBL3094479)
Affinity DataIC50:  10nMAssay Description:Inhibition of glucocorticoid receptor (unknown origin) expressed in baculovirus-infected insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444400(CHEMBL3094479)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of progesterone receptor (unknown origin) expressed in baculovirus-infected insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444400(CHEMBL3094479)
Affinity DataIC50:  190nMAssay Description:Inhibition of mineralocorticoid receptor (unknown origin) expressed in baculovirus-infected insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444400(CHEMBL3094479)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at glucocorticoid receptor in human foreskin fibroblasts assessed as IL-1-mediated IL-6 synthesis after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed