BDBM50444549 CHEMBL3099695

SMILES Fc1cc(ccc1[C@H]1CCc2cncn12)C#N

InChI Key InChIKey=USUZGMWDZDXMDG-CYBMUJFWSA-N

Data  30 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50444549   

TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human aldosterone synthase expressed in V79 MZ cellsMore data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)
Affinity DataIC50:  856nMAssay Description:Inhibition of CYP19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZ cellsMore data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [14C]-deoxycorticosterone substrate incubated for 6 hrs by HPTLC methodMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [14C]-deoxycorticosterone substrate incubated for 6 hrs by HPTLC methodMore data for this Ligand-Target Pair