BDBM50444584 CHEMBL3099718::US9340549, 95

SMILES CC1(C)OC(=O)N([C@H]1c1ccccc1)[C@H]1CC[C@@H](CC1)c1cnc(N)c(c1)C#N

InChI Key InChIKey=SOHHQHWGZGODEC-YSSFQJQWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50444584   

TargetPoly [ADP-ribose] polymerase tankyrase-1 [1091-1325](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM50444584(CHEMBL3099718 | US9340549, 95)
Affinity DataIC50:  6.98nMT: 2°CAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50444584(CHEMBL3099718 | US9340549, 95)
Affinity DataIC50: >8.50E+4nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50444584(CHEMBL3099718 | US9340549, 95)
Affinity DataIC50: >1.70E+5nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed