BDBM50449137 CHEMBL3127163

SMILES OC(=O)c1csc(n1)-n1nc(-c2ccccc2)c2ccc(cc12)C(F)(F)F

InChI Key InChIKey=JELFUQAHMVGHOB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50449137   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50449137(CHEMBL3127163)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50449137(CHEMBL3127163)
Affinity DataIC50:  8.26E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50449137(CHEMBL3127163)
Affinity DataIC50:  0.600nMAssay Description:Antagonist activity at EP1 receptor (unknown origin) by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50449137(CHEMBL3127163)
Affinity DataIC50:  5.53E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50449137(CHEMBL3127163)
Affinity DataIC50:  7.86E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed