BDBM50451153 CHEMBL2303696::Glucuronide Conjugate Of 5-Hydroxy Rofecoxib

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1O[C@@H]1O[C@H]([C@@H](O)[C@H](O)[C@@H]1O)C(O)=O)c1ccccc1

InChI Key InChIKey=LHTQNDXIYIUWMV-JJCLBSHFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50451153   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50451153(CHEMBL2303696 | Glucuronide Conjugate Of 5-Hydroxy...)
Affinity DataIC50: >3.30E+4nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50451153(CHEMBL2303696 | Glucuronide Conjugate Of 5-Hydroxy...)
Affinity DataIC50: >1.00E+5nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed