BDBM50451622 CHEMBL4218185
SMILES O=CCNC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1
InChI Key InChIKey=HGCGAOORAMFLTO-KRWDZBQOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50451622
Affinity DataKi: 7.90nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-phe-Arg-7-amido-4-methylcoumarin as substrate by fluorometric methodMore data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development
Curated by ChEMBL
Roche Pharma Research And Early Development
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assayMore data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development
Curated by ChEMBL
Roche Pharma Research And Early Development
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair