BDBM50454124 CHEMBL3780822
SMILES Cc1c(CN2CCC(CC2)Nc2ncnc3sc(CC(F)(F)F)cc23)ccc2n(Cc3cn[nH]c3)c(cc12)C#N
InChI Key InChIKey=DETOMBLLEOZTMZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50454124
Affinity DataIC50: 15nMAssay Description:Displacement of FITC-MBM1 from full length human menin measured after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to human Menin expressed in Escherichia coli Rosetta2 (DE3) cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 9.30nMAssay Description:Binding affinity to menin (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair