BDBM50455992 CHEBI:3687::Chrysophanol
SMILES Cc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1
InChI Key InChIKey=LQGUBLBATBMXHT-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50455992
Affinity DataIC50: 1.80E+4nMAssay Description:Compound was tested for the enzyme inhibitory activity against Human Leukocyte Elastase (HLE) at 28 uM concentrationMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataIC50: 4.62E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of acid-mediated aggregation of TTR V30M mutant (unknown origin) expressed in Escherichia coli pretreated for 30 mins at pH 7 followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.94E+5nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataIC50: 1.81E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataIC50: 3.61E+4nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair