BDBM50456370 CHEMBL4211185

SMILES Nc1ncnc2n(nc(-c3ccc(Br)c(O)c3)c12)C1CCc2ccccc12

InChI Key InChIKey=ARUHNGYBTHMQAU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50456370   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50456370(CHEMBL4211185)
Affinity DataIC50:  155nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50456370(CHEMBL4211185)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of human recombinant FLAG-tagged full length ATR expressed in mammalian cell line co-expressing human recombinant cMyc-tagged full length ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50456370(CHEMBL4211185)
Affinity DataIC50:  123nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed