BDBM50457306 CHEMBL4202865

SMILES CC(C)Oc1ccc(CO)cc1Nc1nccc(n1)-c1cc2c(NC[C@]2(C)CO)c(c1)C#N

InChI Key InChIKey=RISSKZZAQYAEKW-RUZDIDTESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457306   

TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50457306(CHEMBL4202865)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of recombinant human GST-tagged MAP3K14 autophosphorylation after 1 hr by Alpha screen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50457306(CHEMBL4202865)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of MAP3K14 in human L363 assessed as decrease in IKKalpha phosphorylation level after 2 hrs by sandwich immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed