BDBM50457417 CHEMBL4214015

SMILES COc1ccc(cn1)[C@@H](Oc1ccc(C#N)c(Cl)c1)[C@H](C)NC(=O)C(C)(F)F

InChI Key InChIKey=ADTCHDOIIJGUKX-GTNSWQLSSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50457417   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50457417(CHEMBL4214015)
Affinity DataIC50:  9.30nMAssay Description:Transrepression activity at glucocorticoid receptor (unknown origin) expressed in human ChaGoK1 cells assessed as inhibition of PMA-stimulated gene e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50457417(CHEMBL4214015)
Affinity DataEC50:  33nMAssay Description:Transactivation activity at glucocorticoid receptor (unknown origin) expressed in human ChaGoK1 cells incubated for 24 hrs by beta-galactosidase repo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50457417(CHEMBL4214015)
Affinity DataIC50: <4nMAssay Description:Displacement of fluormone RED from human full length glucocorticoid receptor after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed