BDBM50457418 CHEMBL4208799
SMILES C[C@H](NC(=O)C(C)(F)F)[C@H](Oc1ccc(cc1Cl)C#N)c1cnc(nc1)C1CC1
InChI Key InChIKey=VJZCEJWGTIWTDB-GTNSWQLSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50457418
Affinity DataIC50: 7.80nMAssay Description:Transrepression activity at glucocorticoid receptor (unknown origin) expressed in human ChaGoK1 cells assessed as inhibition of PMA-stimulated gene e...More data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Transactivation activity at glucocorticoid receptor (unknown origin) expressed in human ChaGoK1 cells incubated for 24 hrs by beta-galactosidase repo...More data for this Ligand-Target Pair
Affinity DataIC50: <4.10nMAssay Description:Displacement of fluormone RED from human full length glucocorticoid receptor after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair