BDBM50457423 CHEMBL4209337
SMILES CC[C@H](NC(=O)C(F)(F)F)[C@H](Oc1ccc(cc1Br)C#N)c1cnc(nc1)C1CC1
InChI Key InChIKey=XGORDNAQWNGCSW-DOTOQJQBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50457423
Affinity DataIC50: 9.60nMAssay Description:Transrepression activity at glucocorticoid receptor (unknown origin) expressed in human ChaGoK1 cells assessed as inhibition of PMA-stimulated gene e...More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Antagonist activity at glucocorticoid receptor (unknown origin) expressed in human ChaGoK1 cells assessed as inhibition of dexamethasone induced tran...More data for this Ligand-Target Pair
Affinity DataEC50: 54nMAssay Description:Transactivation activity at glucocorticoid receptor (unknown origin) expressed in human ChaGoK1 cells incubated for 24 hrs by beta-galactosidase repo...More data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Displacement of fluormone RED from human full length glucocorticoid receptor after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair