BDBM50457616 CHEMBL4218628

SMILES O=S1(=O)NCN(C2CC2)c2cc(CCc3ccc4c(c3)N(CNS4(=O)=O)C3CC3)ccc12

InChI Key InChIKey=TVWVZMLPANTKEA-UHFFFAOYSA-N

Data  2 EC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457616   

TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Liege

Curated by ChEMBL
LigandPNGBDBM50457616(CHEMBL4218628)
Affinity DataEC50:  1.26nMAssay Description:Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Liege

Curated by ChEMBL
LigandPNGBDBM50457616(CHEMBL4218628)
Affinity DataEC50:  1.30nMAssay Description:Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB