BDBM50457730 CHEMBL4207331

SMILES COc1cc2c(NC3C4CCC3CN(C)C4)cc(nc2cc1OCCCN1CCCC1)-c1ccc(C)o1

InChI Key InChIKey=KXENQCUVSMIIGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457730   

TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Wuxi Apptec (Tianjin) Co.

Curated by ChEMBL
LigandPNGBDBM50457730(CHEMBL4207331)
Affinity DataIC50:  41nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Tianjin) Co.

Curated by ChEMBL
LigandPNGBDBM50457730(CHEMBL4207331)
Affinity DataIC50:  235nMAssay Description:Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate after 15 mins in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed