BDBM50459745 CHEMBL4210431

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N(C)C

InChI Key InChIKey=JRIVTLCAZKSBNE-XSTSSERXSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50459745   

TargetProtein ENL(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459745(CHEMBL4210431)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to MBP-tagged human recombinant ENL (489 to 559 residues) incubated for 40 mins by measuring fluorescence polarization by microplate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein AF-9(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459745(CHEMBL4210431)
Affinity DataKi:  160nMAssay Description:Binding affinity to MBP-tagged human recombinant AF9 (487 to 568 residues) incubated for 40 mins by measuring fluorescence polarization by microplate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein AF-9(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459745(CHEMBL4210431)
Affinity DataKi:  170nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein ENL(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459745(CHEMBL4210431)
Affinity DataKi:  1.01E+3nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged ENL (unknown origin) (489 to 559 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein ENL(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459745(CHEMBL4210431)
Affinity DataIC50:  3.60E+3nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged ENL (unknown origin) (489 to 559 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein AF-9(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459745(CHEMBL4210431)
Affinity DataIC50:  1.10E+3nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed