BDBM50460742 CHEMBL4228634
SMILES COc1ccccc1-c1nnc2sc(\C=C\c3ccco3)nn12
InChI Key InChIKey=SDVMNLXLFVWQDH-CMDGGOBGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50460742
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Science And Technology Of China
Curated by ChEMBL
University Of Science And Technology Of China
Curated by ChEMBL
Affinity DataKd: 7.08E+3nMAssay Description:Binding affinity to recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) by surface plasmon resonance...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University Of Science And Technology Of China
Curated by ChEMBL
University Of Science And Technology Of China
Curated by ChEMBL
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) using oligonucleosome as substrate...More data for this Ligand-Target Pair