BDBM50462114 CHEMBL2311600

SMILES [#6]-[#8]-c1ccc(cc1)-[#6](-[#6]-[#7](-[#6])-[#6])[Si;v4]1([#8])[#6]-[#6]-[#6]-[#6]1

InChI Key InChIKey=NPHHKEQIFWZXEX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50462114   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50462114(CHEMBL2311600)
Affinity DataIC50:  707nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells assessed as decrease in [3H]-dopamine reuptake after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50462114(CHEMBL2311600)
Affinity DataIC50:  904nMAssay Description:Inhibition of human SERT expressed in HEK293 cells assessed as decrease in [3H]-serotonin reuptake after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50462114(CHEMBL2311600)
Affinity DataIC50:  275nMAssay Description:Inhibition of human NET expressed in MDCK cells assessed as decrease in [3H]-noradrenaline reuptake after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed