BDBM50462114 CHEMBL2311600
SMILES [#6]-[#8]-c1ccc(cc1)-[#6](-[#6]-[#7](-[#6])-[#6])[Si;v4]1([#8])[#6]-[#6]-[#6]-[#6]1
InChI Key InChIKey=NPHHKEQIFWZXEX-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50462114
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Csir-National Chemical Laboratory
Curated by ChEMBL
Csir-National Chemical Laboratory
Curated by ChEMBL
Affinity DataIC50: 707nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells assessed as decrease in [3H]-dopamine reuptake after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Csir-National Chemical Laboratory
Curated by ChEMBL
Csir-National Chemical Laboratory
Curated by ChEMBL
Affinity DataIC50: 904nMAssay Description:Inhibition of human SERT expressed in HEK293 cells assessed as decrease in [3H]-serotonin reuptake after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Csir-National Chemical Laboratory
Curated by ChEMBL
Csir-National Chemical Laboratory
Curated by ChEMBL
Affinity DataIC50: 275nMAssay Description:Inhibition of human NET expressed in MDCK cells assessed as decrease in [3H]-noradrenaline reuptake after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair