BDBM50464147 CHEMBL256907

SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)n1c(C)nnc1C(C)C)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1ccccc1

InChI Key InChIKey=GSNHKUDZZFZSJB-QUMGSSFMSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50464147   

TargetC-C chemokine receptor type 5(Macaca fascicularis)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50464147(CHEMBL256907)
Affinity DataKi:  0.240nMAssay Description:Displacement of [125I]MIP-1alpha from CCR5 receptor in rhesus monkey membrane incubated for 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50464147(CHEMBL256907)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as inhibition of RANTES-induced calcium flux p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50464147(CHEMBL256907)
Affinity DataIC50:  2.10nMAssay Description:Antagonist activity at CCR5 receptor in human MOLT4 cells transfected with Gqi5 assessed as inhibition of RANTES-induced calcium mobilization incubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed