BDBM50464212 CHEMBL4239886

SMILES C[C@@H](Nc1nc(Nc2ccc(F)c(Cl)c2)nc2c(cccc12)C1=CCN(C)CC1)C1CC1

InChI Key InChIKey=TWZWTEWFVPZONU-OAHLLOKOSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50464212   

TargetSon of sevenless homolog 1(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50464212(CHEMBL4239886)
Affinity DataEC50:  1.10E+3nMAssay Description:Activation of SOS1 in human HeLa cells assessed as increase in RAS-GTP levels after 30 mins by pull-down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed