BDBM50464255 CHEMBL4083687

SMILES [H][C@@]12CN(C[C@]1([H])c1ccccc1N(C)C2=O)S(=O)(=O)c1ccc2OCOc2c1

InChI Key InChIKey=FQODOKMLFCFEMH-HUUCEWRRSA-N

Data  1 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50464255   

TargetGlycine receptor subunit alpha-1/beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50464255(CHEMBL4083687)
Affinity DataEC50:  300nMAssay Description:Positive allosteric modulation of human GlyRalpha1beta assessed as increase in glycine-induced chloride ion flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit alpha-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50464255(CHEMBL4083687)
Affinity DataKd:  70nMAssay Description:Binding affinity to human GlyRalpha3cryst by SPR methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50464255(CHEMBL4083687)
Affinity DataEC50:  370nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed