BDBM50466019 CHEMBL4286251

SMILES Cc1cc(cc(C)c1O)-c1ccc(s1)C(=O)c1cc(F)c(F)c(O)c1F

InChI Key InChIKey=BVLIRXILWDNARH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50466019   

Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Pharmbiotec

Curated by ChEMBL
LigandPNGBDBM50466019(CHEMBL4286251)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate after 20 mins in presence of NAD+ by radio-flow detector bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Pharmbiotec

Curated by ChEMBL
LigandPNGBDBM50466019(CHEMBL4286251)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 using [3H]-E1 as substrate after 10 mins in presence of NADPH by radio-flow detector based analys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Pharmbiotec

Curated by ChEMBL
LigandPNGBDBM50466019(CHEMBL4286251)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Pharmbiotec

Curated by ChEMBL
LigandPNGBDBM50466019(CHEMBL4286251)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstradiol 17-beta-dehydrogenase 2(Mus musculus)
Pharmbiotec

Curated by ChEMBL
LigandPNGBDBM50466019(CHEMBL4286251)
Affinity DataIC50:  58nMAssay Description:Inhibition of mouse microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate after 20 mins in presence of NAD+ by radio-flow detector based analysi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed