BDBM50466158 CHEMBL4290247
SMILES Fc1ccc(CC(=O)Nc2cncc(c2)-c2cc(cs2)-c2cccnc2)cc1
InChI Key InChIKey=GLCIBEGENZSGCS-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50466158
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of Dyrk1A in human HeLa cells transfected with GFP-SF3b1-NT assessed as decrease in SF3B1 phosphorylation at Thr434 after 18 hrs by Wester...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant full length human Dyrk1A expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATPMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21(DE3) using KKISGRLSPIMTEQ-NH2 as substrate after 15 ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human Haspin expressed in Baculovirus expression system by Adapta assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human Dyrk1A expressed in Baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
German University In Cairo
Curated by ChEMBL
German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 383nMAssay Description:Inhibition of recombinant full length human Dyrk1B expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATPMore data for this Ligand-Target Pair