BDBM50468128 CHEMBL4282052

SMILES OC(=O)C(F)(F)F.CCOc1cc(CN2CCC3(CN(C(=O)C3)c3ccc(cc3)C(O)=O)CC2)cc(OCC)c1-c1ccc(F)cc1

InChI Key InChIKey=BLQCUVNVAODGCA-UHFFFAOYSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50468128   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human SSTR2 expressed in CHO-K1 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of prostanoid DP receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human SSTR3 expressed in CHO-K1 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E member 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of IKs (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50:  2.10nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from mouse SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of Cav1.2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human SSTR4 expressed in CHO-K1 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50:  1.20nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from human SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity at human SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50:  0.900nMAssay Description:Antagonist activity at mouse SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of MK-499 binding to human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human SSTR1 expressed in CHO-K1 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed