BDBM50468462 CHEMBL4287117::US10968163, Compound 3g::US20230365488, Compound 1z

SMILES OC(=O)[C@H]1[C@@H]([C@@H]([C@H]1c1ccccc1)C(=O)Oc1ccccc1-c1ccccc1)c1ccccc1

InChI Key InChIKey=SCWNEAXNTDXLIY-LJWNLINESA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50468462   

TargetFatty acid-binding protein 5(Homo sapiens (Human))
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM50468462(CHEMBL4287117 | US10968163, Compound 3g | US202303...)
Affinity DataKi:  80nMAssay Description:FABP5 was purified and delipidated as described previously (Kaczocha, M. et al. 2012). FABP5 (30 μg), NBD-stearate (1 μM), and a competitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid-binding protein, brain(Homo sapiens)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM50468462(CHEMBL4287117 | US10968163, Compound 3g | US202303...)
Affinity DataKi:  120nMAssay Description:FABP5 was purified and delipidated as described previously (Kaczocha, M. et al. 2012). FABP5 (30 μg), NBD-stearate (1 μM), and a competitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid-binding protein, brain(Homo sapiens)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM50468462(CHEMBL4287117 | US10968163, Compound 3g | US202303...)
Affinity DataKi:  350nMAssay Description:Displacement of ANS from recombinant human N-terminal His-tagged FABP7 expressed in Escherichia coli BL21(DE3) after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, brain(Homo sapiens)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM50468462(CHEMBL4287117 | US10968163, Compound 3g | US202303...)
Affinity DataKi:  350nMAssay Description:Purified FABPs (3 μM) were incubated with fluorescent probe (500 nM) in 30 mM Tris, 100 mM NaCl buffer (pH 7.5). Compounds to be tested were the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid-binding protein, heart(Homo sapiens (Human))
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM50468462(CHEMBL4287117 | US10968163, Compound 3g | US202303...)
Affinity DataKi:  420nMAssay Description:FABP5 was purified and delipidated as described previously (Kaczocha, M. et al. 2012). FABP5 (30 μg), NBD-stearate (1 μM), and a competitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFABP3 protein(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM50468462(CHEMBL4287117 | US10968163, Compound 3g | US202303...)
Affinity DataKi:  700nMAssay Description:Purified FABPs (3 μM) were incubated with fluorescent probe (500 nM) in 30 mM Tris, 100 mM NaCl buffer (pH 7.5). Compounds to be tested were the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid-binding protein, heart(Homo sapiens (Human))
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM50468462(CHEMBL4287117 | US10968163, Compound 3g | US202303...)
Affinity DataKi:  700nMAssay Description:Displacement of DAUDA from recombinant human N-terminal His-tagged FABP3 expressed in Escherichia coli BL21(DE3) after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5(Homo sapiens (Human))
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM50468462(CHEMBL4287117 | US10968163, Compound 3g | US202303...)
Affinity DataKi:  770nMAssay Description:Displacement of DAUDA from recombinant human N-terminal His-tagged FABP5 expressed in Escherichia coli BL21(DE3) after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5(Homo sapiens (Human))
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM50468462(CHEMBL4287117 | US10968163, Compound 3g | US202303...)
Affinity DataKi:  770nMAssay Description:Purified FABPs (3 μM) were incubated with fluorescent probe (500 nM) in 30 mM Tris, 100 mM NaCl buffer (pH 7.5). Compounds to be tested were the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent