BDBM50471871 CHEMBL135304

SMILES CCOc1ccc2C(=O)C(Cc3ccncc3)(C(=O)c2c1)c1ccc(OC)c(OC2CCCC2)c1

InChI Key InChIKey=NPKPWDGUSZJCEL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50471871   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sw 8 Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50471871(CHEMBL135304)
Affinity DataKi:  20nMAssay Description:Binding affinity at Phosphodiesterase 4 by measuring displacement of (+/-)-[3H]- Rolipram to guinea pig brain membranes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sw 8 Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50471871(CHEMBL135304)
Affinity DataIC50:  12nMAssay Description:Concentration to inhibit 50% of Phosphodiesterase 4 (PDE-4) from guinea pig macrophagesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed