BDBM50471875 CHEMBL335970

SMILES COc1ccc(cc1OC1CCCC1)C1(Cc2ccncc2)Cc2cc(OCc3ccccc3)ccc2C1=O

InChI Key InChIKey=QBJZJLGONNMMNS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50471875   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sw 8 Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50471875(CHEMBL335970)
Affinity DataKi:  60nMAssay Description:Binding affinity at Phosphodiesterase 4 by measuring displacement of (+/-)-[3H]- Rolipram to guinea pig brain membranes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sw 8 Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50471875(CHEMBL335970)
Affinity DataIC50:  20nMAssay Description:Concentration to inhibit 50% of Phosphodiesterase 4 (PDE-4) from guinea pig macrophagesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed