BDBM50477325 CHEMBL248089

SMILES Cc1ccc(cc1)S(=O)(=O)n1c2ccccc2c2ccc(OCC(O)=O)cc12

InChI Key InChIKey=CFUDBEWJWALWEI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50477325   

TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University Of Technology

Curated by ChEMBL
LigandPNGBDBM50477325(CHEMBL248089)
Affinity DataIC50:  3.90E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta42 formation LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University Of Technology

Curated by ChEMBL
LigandPNGBDBM50477325(CHEMBL248089)
Affinity DataIC50:  1.30E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in Amyloid beta-38 formation by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University Of Technology

Curated by ChEMBL
LigandPNGBDBM50477325(CHEMBL248089)
Affinity DataIC50: >4.00E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta-40 formation LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed