BDBM50480563 CHEMBL561448

SMILES COc1c(C)cnc(CN2CC(OC3CCCC3)=Nc3c(Cl)nc(N)nc23)c1C

InChI Key InChIKey=MKBWNXUGDUFIHX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50480563   

TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Poniard Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50480563(CHEMBL561448)
Affinity DataIC50:  10nMAssay Description:Inhibition of HSP90 in human SKBR3 cells assessed as induction of Her2 degradationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed