BDBM50484309 CHEMBL1837047
SMILES Fc1ccccc1C1CC2Cc3[nH]ncc3C(C1)N2S(=O)(=O)c1ccc(nc1)C(F)(F)F
InChI Key InChIKey=KYMTURMJKPIJCE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50484309
Affinity DataIC50: 4nMAssay Description:Inhibition of gamma-secretase-mediated cleavage of amyloid precursor protein in human IMR32 cells after 2 hrs using MBPC-125 substrate by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of gamma-secretase-mediated notch cleavage in human SNC-204B8 cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair