BDBM50485675 CHEMBL2153510

SMILES COc1n[nH]c2ncc(NC(=O)c3c(F)ccc(NC(=O)c4cccc(c4)C(C)(C)C#N)c3F)cc12

InChI Key InChIKey=BCTNUFBSYWOHHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50485675   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50485675(CHEMBL2153510)
Affinity DataIC50:  180nMAssay Description:Inhibition of B-Raf V600E mutant in human Malme-3M cells assessed as ERK phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50485675(CHEMBL2153510)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of full length B-Raf V600E mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed