BDBM50485677 CHEMBL2153514
SMILES COc1n[nH]c2ncc(NC(=O)c3cccc(NC(=O)c4cccc(c4)C(C)(C)C#N)c3)cc12
InChI Key InChIKey=KTFLVJHECROJBK-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50485677
Affinity DataIC50: 140nMAssay Description:Inhibition of B-Raf V600E mutant in human Malme-3M cells assessed as ERK phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of full length B-Raf V600E mutantMore data for this Ligand-Target Pair