BDBM50487061 (3,5-Dichlorophenylamino)Methylenediphosphonic Acid

SMILES OP(O)(=O)C(Nc1cc(Cl)cc(Cl)c1)P(O)(O)=O

InChI Key InChIKey=ALPQLQJFTUXTFT-UHFFFAOYSA-N

Data  5 KI  5 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50487061   

TargetGlutamine synthetase, chloroplastic(Zea mays)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487061((3,5-Dichlorophenylamino)Methylenediphosphonic Aci...)
Affinity DataKi:  6.40E+3nMAssay Description:Un-competitive inhibition of Zea mays cv. Jeff (maize) leaf glutamine synthetase using ATP as substrate Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetGlutamine synthetase, chloroplastic(Zea mays)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487061((3,5-Dichlorophenylamino)Methylenediphosphonic Aci...)
Affinity DataKi:  7.20E+3nMAssay Description:Non-competitive inhibition of Zea mays cv. Jeff( maize) leaf glutamine synthetase using L-glutamate as substrate Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPyrroline-5-carboxylate reductase(Arabidopsis thaliana)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487061((3,5-Dichlorophenylamino)Methylenediphosphonic Aci...)
Affinity DataKi:  1.03E+4nMAssay Description:Uncompetitive inhibition of Arabidopsis thaliana P5C reductase by Dixon plotMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPyrroline-5-carboxylate reductase(Arabidopsis thaliana)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487061((3,5-Dichlorophenylamino)Methylenediphosphonic Aci...)
Affinity DataKi:  1.99E+5nMAssay Description:Noncompetitive inhibition of Arabidopsis thaliana P5C reductase by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPyrroline-5-carboxylate reductase(Arabidopsis thaliana)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487061((3,5-Dichlorophenylamino)Methylenediphosphonic Aci...)
Affinity DataKi:  2.30E+5nMAssay Description:Noncompetitive inhibition of Arabidopsis thaliana P5C reductase by Lineweaver-Burk plot in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetGlutamine synthetase, chloroplastic(Zea mays)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487061((3,5-Dichlorophenylamino)Methylenediphosphonic Aci...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of Zea mays cv. Jeff (maize) leaf glutamine synthetase using L-glutamate as substrate assessed as inorganic phosphate production after 20 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetGlutamine synthetase, chloroplastic(Zea mays)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487061((3,5-Dichlorophenylamino)Methylenediphosphonic Aci...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of Zea mays cv. Jeff (maize) leaf glutamine synthetase using L-glutamate as substrate assessed as inorganic phosphate production after 20 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPyrroline-5-carboxylate reductase(Arabidopsis thaliana)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487061((3,5-Dichlorophenylamino)Methylenediphosphonic Aci...)
Affinity DataIC50:  7.69E+4nMAssay Description:Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPyrroline-5-carboxylate reductase(Arabidopsis thaliana)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487061((3,5-Dichlorophenylamino)Methylenediphosphonic Aci...)
Affinity DataIC50:  7.70E+4nMAssay Description:Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 minMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetGlutamine synthetase(Oryza sativa)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50487061((3,5-Dichlorophenylamino)Methylenediphosphonic Aci...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of Oryza sativa (rice) glutamine synthetaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed