BDBM50492354 CHEMBL2403862
SMILES CC(C)(O)c1nc2cc(Cl)ccc2n1[C@@H]1CC[C@@H](CC1)NC[C@@H]1Cc2ccc(cc2C1)C#N
InChI Key InChIKey=OKRHAYBIIRGRNK-YSZBQJHXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50492354
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Antagonist activity at human MCHR1 expressed in CHOK1 cells assessed as inhibition of MCH/forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Displacement of [125I]MCH peptide from human MCHR1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair