BDBM50497423 CHEMBL3343670

SMILES Cl.[#7]\[#6](-[#7])=[#7]\[#6](=O)-c1ccc2-c3ccccc3C3([#6]-[#6]-[#6]-[#8]3)c2c1

InChI Key InChIKey=VZIRLMPZNVYXDY-UHFFFAOYSA-N

Data  7 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50497423   

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50497423(CHEMBL3343670)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]5-HT from human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50497423(CHEMBL3343670)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50497423(CHEMBL3343670)
Affinity DataKi:  152nMAssay Description:Binding affinity to serotonin 5-HT2C receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50497423(CHEMBL3343670)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50497423(CHEMBL3343670)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to alpha1-adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50497423(CHEMBL3343670)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to muscarinic M5 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50497423(CHEMBL3343670)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to serotonin 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50497423(CHEMBL3343670)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in CHO cells assessed as cAMP production by EIA systemMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50497423(CHEMBL3343670)
Affinity DataIC50:  55nMAssay Description:Antagonist activity at human 5-HT2B receptor expressed in HEK293 cells assessed as [3H]PI metabolismMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed